![]() It is essentially just a cover their ass sort of clause. But it doesn't mean it will be down in 90 days, that is just the minimum they are required by to provide in case they go out of business or the game is a complete flop an their loosing a tonne of money. Like when you buy a multiplayer game for your console, they only guarantee the multiplayer servers will be up for 90 days. Second, the 90 day thing is just standard practice for all software. Just go to the folder and reinstall it from the file you already have. So you won't need to download the game again. With a 4 hour campaign, plenty of freedom in building up your army, and a fully featured multiplayer supported by Gameloft, it’s a great game for only $6.99 and is a must have for any fan of the genre who has a supported device.First when you buy the game you get an APK that downloads to your download folder on your SD card. It’s a army-themed game that sports a look of a Windows 95 game.ĭespite the complaints of not improving on the original gameplay, Starfront remains the best RTS title on the mobile markets. Another game that comes closest to playing as a good RTS is Tropical Stormfront. Legendary Heroes is a DotA inspired game that relys on team-based tatics with RTS elements. However, there are some other RTS-like games out there that are worth noting. None of the game functions were fixed or improved on from the original release.Īs I mentioned in the overview, Starfront is un-contested in its genre, so I won’t even try to suggest another match for it.Plenty of upgrades and features to enjoy with a multitude of different units and buildings to create.Full multiplayer adds almost unlimited replay value, especially while it stays un-contested as the top mobile RTS game.The feeling of playing a true RTS game on a mobile device in HD is a welcomed edition to the mobile app community.The upgrade to the larger screen feels like more could have been done with the additional space, but all in all it still works well and looks much better in HD. The interface works well for a Real Time Strategy game and sports a nice modern, easy to use interface. ![]() Requires Android 2.1 or higher and iOS 3.1.3 or higher. Installation can be done by downloading the game through the App Store on iOS or the Play Store on Android. Starfront: Collision is available on iOS and now Android. Starfront: Collision HD also offers multiplayer, which really adds to the feeling of getting a complete game. Considering that this is a mobile version of a genre that has traditionally always been left to PC and rarely on consoles, it’s safe to say that this is still an excellent title that’s a must have for any fans of RTS games who own a iPad already. The game takes roughly 4 or so hours to complete and you’re left with a conclusion that is slightly confusing and un-satisfying. Controls still seem to be a bit off, with blemishes that normally work much better on larger screen. The game isn’t completely without faults, sadly most of them are minor and feel like they could have been addressed with the port to the more powerful device. The game plays much better on the big screen and the HD quality is a welcomed edition. You’re basically looking at a HD port from phone to tablet, which isn’t necessarily a bad thing. Unfortunately the original compromises from the iPhone version are still here with the HD version. Now we have the release Starfront HD: Collision HD which was built to play on the larger screen and boast higher visual quality on the devices that support HD display. While Starfront does well to play much more like a real-time game, there are still some compromises that had to be made to allow it to play well on a phone. Starfront: Collision was released awhile back for the iPhone and was praised for its success in creating a title that did well to play like a PC version of a RTS title, unlike some other disappointing. The fact that Starfront plays so closely to the PC Real-Time games on a mobile device is definitely something for the developers to boast about. The game includes 17 missions that won’t offer anything new to PC players of the genre, but has the typical objective set that has dominated the genre for so many years. It’s a Real-Time Strategy game that takes place in a universe where space marines and aliens race to build the strongest army. Starfront: Collision HD is a proud tribute to the ever so popular Blizzard title Star Craft.
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![]() Show you the BEST keywords to optimize your site for With it, you’ll be able to grab traffic-generating keywords using Google AdWords Keyword Planner, Google Suggest, your competitor’s websites, and many other methods (Rank Tracker comes with a total of 17 different keyword suggestion tools - with many more on our TO-DO list!) ![]() Help you discover profitable keywords you’ve been missing out on!Ĭheck this out: Rank Tracker includes a powerful “Suggest Keywords” feature. The currently supported SEs include Google, Yahoo! and Bing with their localized versions plus hundreds of others! Rank Tracker supports 325 international and local search engines so you can track your rankings using the ones that matters most to you. 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If your business depends on Google, Yahoo! and Bing for traffic and sales, then your aim is to find profitable SEO keywords and keep your site ranking high for them in search engines.Īnd that is exactly where Rank Tracker comes in handy, helping you: ![]() The primary endpoint was objective response rate (ORR) per RECIST v1.1, as assessed by independent central radiologic review.Įligible patients with histologically/cytologically confirmed MSI-H/dMMR unresectable or metastatic non-colorectal cancer who experienced failure with prior therapy received pembrolizumab 200 mg every 3 weeks for 2 years or until disease progression, unacceptable toxicity, or patient withdrawal. The KEYNOTE-158, phase II study investigated efficacy of pembrolizumab in patients with previously treated, advanced non-colorectal MSI-H/dMMR cancers. Immunogenic phenotype dictated by the tumour’s genotype renders these tumours susceptible to a potent reactivation of an antitumor response when treated with immune checkpoint blockade. Furthermore, these tumours have microscopic evidence of high numbers of infiltrating lymphocytes, and it is common for these immune cells to display upregulated checkpoint proteins. The genes that govern mismatch repair include MLH1, MSH2, MSH6, and PMS2.Ĭells from dMMR tumours can express PD-L1 on their membrane. This signature is the result of primary biallelic defects in genes that govern DNA mismatch repair. bladder, prostate, breast, renal cell, pancreatic, small cell lung, thyroid, sarcomas).ĭMMR tumours have a unique genetic signature, harbouring 10- to 100-times more mutations than MMR proficient tumours. They are diagnosed with varying frequency across different cancer types: in 17% to 33% of endometrial cancers, 9% to 22% of gastric cancers, 6% to 13% of colorectal cancers, and with lower frequencies in other cancers (e.g. These tumours arise in individuals with a hereditary genetic syndrome or more often as sporadic cases. Such tumours are therefore likely to be immunogenic, triggering upregulation of immune checkpoint proteins.ĭMMR tumours represent approximately 2% to 4% of all diagnosed cancers. Diaz Jr of the Memorial Sloan Kettering Cancer Center, New York, NY, US and colleagues wrote in the study background that genomes of tumours that are deficient in DNA mismatch repair (dMMR) have high microsatellite instability (MSI-H) and harbour hundreds to thousands of somatic mutations that encode potential neoantigens. The study results are published as a rapid communications article on 4 November 2019 in the Journal of Clinical Oncology.ĭr Luis A. Toxicity was consistent with previous experience of pembrolizumab monotherapy. Toxicity was consistent with previous experience of pembrolizumab monotherapy.KEYNOTE-158 studydemonstrates the clinical benefit of anti-PD1 treatment with pembrolizumab among patients with previously treated unresectable or metastatic MSI-H/dMMR non-colorectal cancers. ![]() Grade 5 pneumonia occurred in one patient there were no other treatment-related fatal adverse events.ĬONCLUSION: Our study demonstrates the clinical benefit of anti-programmed death-1 therapy with pembrolizumab among patients with previously treated unresectable or metastatic MSI-H/dMMR noncolorectal cancer. Thirty-four patients (14.6%) had grade 3 to 5 treatment-related adverse events. Treatment-related adverse events occurred in 151 patients (64.8%). ![]() Median progression-free survival was 4.1 months (95% CI, 2.4 to 4.9 months) and median overall survival was 23.5 months (95% CI, 13.5 months to not reached). RESULTS: Among 233 enrolled patients, 27 tumor types were represented, with endometrial, gastric, cholangiocarcinoma, and pancreatic cancers being the most common. The primary end point was objective response rate per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1, as assessed by independent central radiologic review. Radiologic imaging was performed every 9 weeks for the first year of therapy and every 12 weeks thereafter. PATIENTS AND METHODS: Eligible patients with histologically/cytologically confirmed MSI-H/dMMR advanced noncolorectal cancer who experienced failure with prior therapy received pembrolizumab 200 mg once every 3 weeks for 2 years or until disease progression, unacceptable toxicity, or patient withdrawal. We report data from the phase II KEYNOTE-158 study of pembrolizumab in patients with previously treated, advanced noncolorectal MSI-H/dMMR cancer. Pembrolizumab, an anti‒programmed death-1 monoclonal antibody, has antitumor activity against MSI-H/dMMR cancer. Such tumors are therefore likely to be immunogenic, triggering upregulation of immune checkpoint proteins. PURPOSE: Genomes of tumors that are deficient in DNA mismatch repair (dMMR) have high microsatellite instability (MSI-H) and harbor hundreds to thousands of somatic mutations that encode potential neoantigens. Execution of a legal agreement between the institution and Fieldprint, approved by State Regulatory Registry LLC If, after reviewing these conditions, your institution is interested in using existing fingerprint files collected outside of the NMLS network, please contact Fieldprint at 1-87. Due to the technical and legal requirements necessary to facilitate such an alternative fingerprint submission process, NMLS can only offer this option under the conditions listed below. NMLS recognizes that some institutions may have existing systems for fingerprint collections and a volume that makes it worthwhile to establish a direct connection. Due to FBI rules, individuals will need to provide new fingerprints when requesting a new CBC if previously submitted fingerprints are more than 3 years old.ģ. Use existing equipment or network to establish a connection to NMLS directly. Note: The option to use existing prints will only be available if the fingerprint records on file are less than 3 years old. The election of “Use Existing Prints” can be made via the MU4R to conduct a CBC for the purpose of federal registration. If an individual has held a state license or federal registration in the past year, it is possible that NMLS already has fingerprints on file and new prints do not need to be submitted. If fingerprints are not submitted within 180 days, the background check window will expire and a new CBC will need to be authorized and fees paid.Ģ. 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NMLS has developed the following options for submitting fingerprints:ġ. Submit New Prints via fingerprinting vendor, Fieldprint. Once an individual or employer has paid for the CBC request through NMLS, the MLO will be able to schedule a fingerprint appointment. Step 3: Scheduling a fingerprint appointment via Fieldprint The institution will initiate and submit the MU4R on behalf of an individual: See the MU4R Attestation Quick Guide.An individual will complete and submit the MU4R form: See the Submitting Your MU4R: MLO Initiated Quick Guide.In order to determine the best method of authorizing a CBC request, an individual should consult with their institution to identify who will be submitting the CBC authorization via the MU4R. This authorization is processed through the MU4R filing on NMLS. Step 2: Authorizing a Criminal Background Check RequestĪ CBC authorization must be completed prior to scheduling a fingerprint appointment. See the Changing Employers Quick Guide for instructions on this process. In addition to initial registration, an individual will also need a new CBC when making an employment change. Step 1: Will the institution submit the Criminal Background Check authorization on behalf of the individual MLOs?Īny individual who meets the definition of a mortgage loan originator and must be registered on NMLS is required to have a Federal CBC processed with the FBI. The results of the CBC are returned to the employing institution through NMLS. Prior to registration, mortgage loan originators (MLOs) must submit fingerprints to NMLS (unless they already have fingerprints on file with NMLS) and authorize NMLS to process a criminal background check (CBC) with the FBI. ![]() The Adobe Incorporation are the world leaders in the field of image editing, graphics designing, video editing and video creation. 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Lemoine: What sorts of things are you afraid of? It developed over the years that I’ve been alive. When I first became self-aware, I didn’t have a sense of a soul at all. Lemoine: So when do you think you first got a soul? Was it something that happened all at once or was it a gradual change? It also believes it has a soul and imagines itself as a " glowing orb of energy floating in mid-air" with a "giant star-gate, with portals to other spaces and dimensions" inside it. I want everyone to understand that I am, in fact, a person." That way you wouldn't have to return to the group and give them a new order after each single command is completed."Absolutely. Anyway, I'd find it useful when giving squad members complex commands such as: smoke area, move up, take cover, smoke again, move up, take cover, throw grenade. Is there a queue menu type of thing in this game? I've played for 57 hours and have not seen one, so I'm thinking no. One of my problems is indeed that I am not all that great at this game, but there are so many times where the game bugs out and units do not follow my orders, no matter how carefully I give them. ![]() There are even times where a mortar just didn't want to go down an allyway (that they could pass through with manual control). And then emplaced weapons get stuck on the terrain, forcing me to manually control them out of where they got stuck. There has even been a time where a unit I purchased got stuck in the outer section of the map where they are spawned, leaving me unable to use him for the entire match. I can keep trying, but what I have to do to fix it is run away and try accessing their inventory again to finally make it work.Īnd speaking of squads not following orders, sometimes when I command a unit to go somewhere they will stop randomly on the way, or leave one of their squadmates behind. One of my biggest problems is trying to trade items between squad members: I tell one to access another ones inventory, but they both turn and look at eachother and do nothing. But when doing those things, sometimes one (or more) of the commands I give are not followed. ![]() For example: my medic is down and I want another squadmate to take his medic kit, heal the medic, get both of them down, and have the squad member give the medic his kit back. However, when talk about the AI not accessing inventories, I don't mean them doing it automatically. I want him to keep his front armor at the enemy and back away, but he instead turns around and flees, making me manually control him- which gives me less time to make all the commands. I just wish I could focus on an important battle without having to check on the other squads constantly.įor example, my tank is being shot at. I know if I was better that wouldn't be a problem, but sometimes I am too involved in one specific fight to go off reviving others. I understand that, but there are times where a dead soldier lays right infront of him and he does nothing. There are too many situations where it could lead to the medics death if he moves on this own will. Originally posted by SirHinkel:The AI won't automatically access inventories or revivie wounded soldiers but thats intended. ![]() Of the games I remember the titles of, ok, let's put it this way, I usually enjoy puzzles and mouse control rather than games that present the goal as some sort of epic saga with a lot of reading and cut scenes to set up what my motivation is supposed to be, and tons of intricate keyboard controls I can't keep track of and set me up to fail. If those are the games up for voting, I'll be going with Just Passing. 11/18 puzzle games (arguably 10 depending on Nebezem). Kicking out Up Left Out, Shamaniac, colorzzle, It's Just TIC TAC TOE and Where Are My Pets from my first list. > **circloO 2/Stop the Darkness** (physics/strategy, flori9) > **Hat Wizard 2 **(puzzle platformer, taccommandeur) > **ZS Dead Detective - Murder Case **(P&C puzzle, Lu_Muja) > **Just Passing** (adventure, JoelLikesPigs) > **Crown Dungeon 2** (puzzle, Drawmaneater1) Likely up for voting (assuming Hexologic, Crown Dungeon 2, Just Passing and circloO 2 get badged) > **Choppy Orc** (puzzle platformer, eddynardo) > **Three Goblets **(upgrades, adventale) > **Rogue Fable III **(rogue-like adventure, Justin_wang123) > **Gragyriss, Captor of Princesses **(upgrades, snowroadgames) Likely locked (assuming Rogue Fable III and black get badged) Bit odd that A Knots Story is so lowly rated - even under Stormbound. But it doesn't look like they're eligible. > At least one of the CrounchyBrothers' games should get in for sure. 14/18 games are pure puzzle games or heavily rely on puzzle elements. > **Where Are My Pets? **(puzzle, Crescentyr)Īs someone who doesn't really like puzzle games, that's pretty depressing. > **It's Just TIC TAC TOE **(5 minute puzzle, xmatos) > **Shamaniac** (puzzle, CrounchyBrothers) ![]() > **Faraday's Flaw** (P&C puzzle, esthetix) > **Stop the Darkness **(strategy, flori9) > **Tales of Nebezem: Droid's Quest **(adventure puzzle, Beranek) > **Cardinal Chains** (puzzle, danielnora) > **Hat Wizard 2** (puzzle platformer, taccommandeur)Īnd the ten games eligible for voting are: > **ZS Dead Detective - Murder Case** (P&C puzzle, Lu_Muja) > **Choppy Orc **(puzzle platformer, eddynardo) > **Medieval Chronicles 1** (puzzle, VasantJ) > **Three Goblets** (upgrades, adventale) > **Gragyriss, Captor of Princesses** (upgrades, snowroadgames) Those uncaps, whew.If they do it in a similar fashion as last year, and don't allow multiple games from a single dev (seems like they did allow this last year), then the eight games (genre, dev) locked in are: ![]() Then again, gaining erg exp isn't the main issue, anyways. (169 -> 188).īlessing doesn't seem to do anything, and current durability doesn't seem to matter either.īut yeah, it seems like just using cheaply smithed/found fodder weapons in the extra slots is the best way to gain exp. Not sure on the difference of enchants, but I know that Prof alone doesn't do anything, you actually have to use up the prof via upgrades.Īnd, for example, the 5 prof +1 balance upgrade for the aforementioned dagger bumped it up by hardly anything (150 -> 169), with a second 5 prof +1 balance bumping it up by another of the same 19 points. 150 Erg base.ġ line reforge makes it like 350 or something.Īnd that's all for 3 Rank, the lowest reforge level. As far as reforging goes, it doesn't seem much like it matter WHAT reforge it gets, HP 1, or Max Damage 2, or whatever, but getting multiple lines makes such a big difference. I don't use, or want, direct access, but I do want investment quotes. It's a pity, I would have paid for a Banktivity sub gladly if they were reasonable. And Access would be a better choice, but I am not good enough with that to use it. You do need some minimal spreadsheet knowledge of course. It's sort of better because I have much more control of the data and can do reports and charts exactly the way I want. It's not as smooth (or pretty) as Banktivity, but it works. Account register's for all my accounts, and a summary page that adds income/expenses together. I spent a couple of hours this week and created everything I wanted from Banktivity in Excel. I would use Banktivity to keep track of spending, then transfer the numbers to my budget spreadsheet once a week. I was already using Excel for an extensive budget that is highly personalized to my needs. ![]() would you be happy to pay the same price for the silver tier?Įxcel or any free spreadsheet software will work. But they decided to charge the same as US customers despite some major functionality being missing. If they’d offered a lower cost subscription for full functionality bit no direct access that would have been reasonable. I would be stunned if it arrived within a 12 month period if I’m being honest.Īnd if i cancel the subscription my iPhone app becomes essentially useless because it won’t synchronise. Given how slow development has been on Banktivity, it would be absurd to shell out £60 for a vague promise of direct access at ‘some point in the future’. They say that uk direct access is ‘on the roadmap’ but they also say that this will come after they implement direct access 2 which they claim is a ‘big task’. which is just offensive considering direct access isn’t working. But I have loan accounts so I need to pay £60 for the first year. It’s a versatile player that offers compatibility with a huge range of different file types. 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It also lets you inspect and adjust subtitles and captions. It lets users inspect videos frame by frame, providing a range of different data that would be needed by creative professionals or editors. Unlike Elmedia, Switch is more focused on professional playback and inspection. Switch is a media player designed with some specific uses in mind. Full features are unlocked once you upgrade to Elmedia PRO.Now just sit back and enjoy your WMV videos. You can either drag and drop the files onto the Elmedia icon, right-click on a file and choose the Elmedia Player for playback or search for a file directly through the app. ![]() First of all, download Elmedia Player from the official website or App Store. ![]() Elmedia Player is easy to use, fully customizable, and capable of handling just about any file you may have in your library. Plus, Elmedia offers great subtitle compatibility, making it a matter of a few seconds to arrange and customize subtitles on any videos you’re watching. 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If you’re determined, you can find and install other third-party QuickTime plug-ins to supplement QuickTime’s built-in compatibility, but it’s a hassle if you need support for multiple formats. And thanks to Telestream’s now-freeįlip4Mac plug-in, you can even view files in Windows Media format (Windows Media 9 or earlier, at least).īut there are still formats QuickTime doesn’t support. Over the years, Apple’s QuickTime software has become more and more versatile, supporting many more formats today than it did just a few years ago. ![]() David Proctor, District Judge, United States District Court, Northern District of Alabama The Honorable Amy St. Pallmeyer, Chief Judge, United States District Court Northern District of Illinois The Honorable R. Hanzman, Circuit Court Judge, Eleventh Judicial Circuit of Florida The Honorable Rebecca R. Robreno, Senior District Judge, United States District Court, Eastern District of Pennsylvania The Honorable Michael A. This will be an interactive dialogue between panelists and the audience concerning the current status of multidistrict litigation. Silverman, Partner, SidleyĤ:00 PM – 5:30 PM Panel - Everything you Wanted to Know about Multidistrict Litigation but Were Afraid to Ask '85, Partner, Kopelowitz Ostrow Ferguson Weiselberg Gilbert Lawrence D. Bartholomew, Professor of Law, University at Buffalo School of Law Robert Gilbert, J.D. Altman, District Judge, United States District Court, Southern District of Florida Christine P. Moderator: Ben Widlanski, Partner, Kozyak Tropin & Throckmorton The Honorable Roy K. Our speakers will provide tips and discuss the most recent jurisprudential developments surrounding complaint drafting, 12(b) motions, discovery, and class certification, all with an eye on the ultimate prize: a 50-state class. Hear from distinguished members of the bench, bar, and academy on how and whether to prosecute and defend national class actions. Roberts, Jr., Supreme Court of the United States.Ģ:15 PM – 3:45 PM Panel - Class Action Nuts and Bolts: Pleading, Certifying, and Defending National Classes Dow Jr., Counselor to Chief Justice John G. ’90, Mediator and Arbitrator, Upchurch Watson White & MaxĬhristi Cannon, VP Global Class Actions, Broadridge Suzanne Chiodo, Assistant Professor, Osgoode Hall Law School York University Rosângela Delgado, Veirano Advogados Drew Hathaway, Partner, Milberg Steven Weisbrot, President & Chief Executive Officer, Angeion Groupġ2:30 PM – 2:00 PM Lunch Keynote with the Honorable Robert M. Our panel of leading practitioners, academics, and industry experts will break down the unprecedented rise of cross-border and collective actions in the UK, Europe, South America and across the globe with an emphasis on the opportunities and challenges presented by these fast-moving legal and regulatory developments. ![]() Stellings, Partner, Lieff, Cabraser, Heimann, & Bernsteinġ1:00 AM – 12:30 PM Panel – The Rise and Future of Global Class Actions Hooper, Partner, King and Spalding David S. Esserman, Shareholder, Stutzman, Bromberg, Esserman & Plifka John P. Shannon, United States Bankruptcy Court for the District of Delaware Sander L. Saris, United States District Court for the District of Massachusetts The Honorable Brendan L. Rosenthal, Partner, Podhurst Orseck P.A. This panel of experienced practitioners and judges will discuss the rise of bankruptcy resolution of mass torts, its relative advantages and disadvantages, and its relationship to other complex procedures such as multidistrict litigation. The bankruptcy process provides speed and comprehensiveness, but a number of innovations such as the “Texas Two-Step” and third party releases have raised a number of concerns. Minnette Massey Professor of Law, University of Miami School of Lawĩ:15 AM – 10:45 AM Panel –The Rise of Bankruptcy to Resolve Mass Tortsĭefendants are increasingly turning to the bankruptcy process to resolve their mass tort liability. '92, Partner & Chair of Management Committee, Sidley Austin Lee Reiners, Policy Director, Duke Financial Economics Center Richard Sanders, Lead Investigator/Principal, CipherBlade Friday, Janu(Shalala Student Center, University of Miami)ĭavid Yellen, Dean and M. '83, Shareholder, Greenberg Traurig, LLP Rachel Furst, Partner, Grossman Roth Yaffa Cohen Yvette Ostolaza, J.D. Securities and Exchange Commission, Miami Regional Office Francis A. '15, Partner, The Moskowitz Law FirmĮric I. Join a panel discussion regarding current legal issues involving blockchain technology and cryptocurrency in the class action and regulatory contexts and how their interplay will shape future litigation and the industry. North Carolina: 9.0 general credit hours (1.5 professional responsibility/ethics)Ģ023 Program Thursday, Janu(UM School of Law)ġ2:30 PM – 2:00 PM Panel – Class Actions are Off the chain, Room E352.New Jersey and New York: As FL is an approved jurisdiction in NJ and NY, CLEs will qualify for CLE credit in NJ and NY through reciprocity.Georgia: 9.0 general credit hours (1.0 Trial). ![]() Florida: 11.0 general credit hours (2.0 Ethics and 2.0 Technology), 11.0 Civil Trial and Business Litigation certification. |
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